David Armstrong
Moderator
Assuming that the guy with the .22 is unskilled and a bad shot, you are right. However, that is a heck of an assumption. Few opponents (at least in our society) armed with a knife are likely to be particularly skilled, and a moderate level of defensive tactics will allow the shooter the opportunity to engage with his weapon. I've met few that will continue an assault once a few bullets get into them, no matter what the caliber. So there is a fairly good chance of a shooter winning against a close-range knife wielding opponent, and survival rates from cuts are even higher than from gunshots.Against a skilled opponent with a knife at 5-10 feet you with your 22 have zero chance of winning and your chances of surviving the confrontation are actually quite low.
For those that continue to mis-state/mis-use the findings of the Tueller Drill (the 21-foot rule), the drill simply shows that a person can close that distance faster than another person can draw from the holster. It does not mean that you will always lose or any of this other stuff. In fact, it has been shown many times that one has plenty of time to notice a threat and react to the threat, as long as the reaction is one that improves the survival chances. Simply moving off the line of attack works quite well.