My wife has three actually. A Glock 23 that she completed a 600 round defensive handgun course with; a Smith 36 with 3" bbl. that she's had since about '93, and a Smith Bodyguard380 that's around 5 years old.
She's best with the Glock, does almost as good with the Smith 36 .38 Spl., but carries the Smith Bodyguard380 because of its size. That said, she conversant with all of my guns; so whatever we're travelling with, she can use without fumbling, if I'm away from the gun.
Movie nights and dinner on the town, Louisville, I carry, but she's been known to ask if I'm "heeled", in case I forgot.
YMMv Rod