I used to have a Browning Buckmark I really liked. Accurate, looked great, and felt great in my hand--grips molded perfectly. Only issue I had was chambering the first round was pretty hard as that initial slide pull was extraordinarily heavy. Everything else about it was silky smooth, though.
Oh, I don't think it fully opened up, so I had to clean it from the muzzle end, if I recall--that was a bit annoying.
But really, like a couple others have said, I wouldn't companion a .22 pistol with a .22 rifle for going out in the field. If I'm squirrel hunting or something with my .22 rifle, I'll have my .40 pistol at my side in the event I encounter some grumpy critter who wishes to get better acquainted. Conversely, I guess if I were out with a larger caliber rifle, I may want a .22 pistol on me in case I chose to take a squirrel and didn't want it splattered into the next county.