No. Only if you want to make that the case.
your the one that said it. I said shooting a Glock is no problem in a non defensive situation you said it would make a difference who's hand it was in.
I agree grip angle is a problem in both directions. It's also really only a problem under certain circumstances. Grip angle is not a problem if you have plenty of time to line up the sights. IE I can shoot a gun upside down looking between my wrists at the sights, pulling the trigger with my pinky and shoot tight groups given enough time (you also have to hold high). I do not concider this a defensive skill.Part of the problem with this discussion is that it seems that there are people who don't believe that anyone's hands can be different from theirs.
One of the reasons I finally accepted Glocks (the idea of plastic guns with sproingy triggers was not at all attractive when I first looked them over) was because they pointed very naturally for me. I've run into several other guns that point well for me over the years, but the 1911 isn't one of them.