Everybody loves to bad-rap the .25. Granted, there are more powerful options, but anyone who thinks the .25 is non-lethal is talking out of his hat. About ten years ago in Memphis, a law enforcment officer's kid who had some mental problems got ahold of his father's Beretta Mod. 21 in .25 acp. He killed two men and severely wounded another in three separate incidents, three separate days. As far as accuracy, I've owned a Raven, a Jetfire, and a Colt Junior, and all would hold within six inches at 15 yards, and they didn't jam, an advantage of FMJ rounds over lead bullets like the .22 LR.
A lot of the supposed "info" about calibers and effectiveness seen here is like urban legends: it gets repeated often enough and soon everybody believes it. The .25 auto was one of the most popular calibers of the last century. Even if you attribute much of this to the size and affordability of the weapons, it would not have remained so if the bullets just bounced off coats and bodies. I'll take a .25 over a knife or a stick any day.