Being a revolver guy for the most part, it pains me to admit that a good,strike that, a great pistol equipped with a coaxial light, and night sights plus your cell phone will fill your needs. They are the two best defense tools for home and family protection IMHO. You'll also need a plan, and absolute knowledge of your family's whereabouts each and every night.
For us, it's a Sig 226, with the above enhancements on my night stand. When I'm away, my wife uses either her Glock 23 or a S&W M637.
Rod