If your 45 automatic pistol cartridge goes BANG! everytime you drop the hammer on a loaded chamber, the type of bullet you're shooting probably doesn't even matter. It will make a big hole and will probably penetrate adequately.
The question is not what's THEORETICALLY the best cartridge/bullet type you can shoot in a 45 Pistol, it's will the 45 automatic cartridge that you're trying to shoot in YOUR 45 pistol go bang every time you pull the trigger of YOUR pistol, and will the empty brass from that round eject from YOUR pistol every time?
If the answer is yes, shoot whatever you like. If the answer is no, 45 ACP ball ammo may be just what you need, because thats the round that most 45 automatic pistols were built to shoot.