The cautions about keeping your backpack with you is valid. Maybe you have a place to lock it up? If you work out that set of problems, there are also backpacks and sling packs with integral holsters. I would want the trigger covered inside the pack, myself. If you don't buy a concealment pack, you might still be able to figure out a way to attach a holster to your pack. I would also advise dedicating a pocket to the pistol.
Absolutely. I would probably buy a backpack designed to hold the pistol or work out something like a specialized compartment for it. I am very cautious about those types of things. As far as bringing the bag with me, yes it currently goes everywhere, even the bathroom and to meetings and is always either on my back or at my feet.
Having said that, currently I can't even carry at work so this is just wishful thinking. The gun I am getting is really for home defense and hopefully could be used to carry at work in the future if they ever allow it. More than likely I would probably buy another gun at that time anyway, so I am considering just getting a full size pistol for home defense only right now. Going to look tomorrow and check out some guns. Hopefully get to the range soon with some buddies to try to what they are carrying these days too.