From what Ive read here, along with countless hundreds of other threads/posts, the only way to truly keep ANY weapon from failing, at any point in time, is to not fire it at all!! I mean, these are man-made objects, right? Now, its obvious that some are better made than others and have better "track" records. But, as shown many, many times before, even the "best" are capable of failiing, even within a relatively short period of time.
I guess my over-all point would be this....There is only so much that can be done to "try" insuring a weapon will encounter as few, if any, malfunctions as possible. Things such as proper handling, good maintenance practices, regular function testing, using "proper" ammo, purchasing quality weapons to begin with, etc., etc.
Ive shot (only) 500 rounds or so through my Sig without issue. Now, if I run into something later on down the road (I expect I will), say, around the 700-1000 round mark...does this mean I automatically start believing that this gun is unreliable? Heck no.
Frankly, I think Mr.Murphy can show up anytime, anywhere. All you can do is try to decrease the odds that this will happen at the worst possible time. Short of keeping yourself constantly armed with 2 or more weapons (not necessarily practical when speaking of HD), what else can you really do?