A few more blows to the dead horse.
Or at least,questions.If we take three Orcs(bad guys) and put a target dot on each one,from the same angle,hit one with a 9mm,one with a 40,one with a 45.
Each gets one front rib hit,some lung,pulmonary artery,and rear rib,scapula,exit.
I'll agree the more major calibers may feel like being hit with a bigger hammer.
Therefore,our Orc MAY spend 5 seconds going OOOOWW,I got shot with a 9mm,and MAY spend 10 seconds going OOOWWWW I got shot by a 40 or 45.
Blood loss MAY make him drop 4 seconds sooner from the major caliber than from the 9mm.
Might the few seconds advantage from the major caliber matter? Sure.
Are they both going down from a blown pulmonary artery? Yes.
Now,lets assume a liver hit. I'm thinking a liver is a little different.Can't say for sure,but massive "temporary cavitation" in a liver might make messy liver soup. I'd think it would be disabling and pretty lethal.
MAYBE some of the lower vel/harder bullets,likea 230 gr 45,would do more of a pass through.Maybe a higher vel,light bullet loose HP would wreak more havoc. Could be some 40's would excel.Or 357 Sig.
Thighs? Butt cheeks? Lower abdomen?
Each portion of anatomy will present a different situation.
First job,punching a hole through.First round,they are ALL THE SAME for accuracy/shot placement.
First round impact on target? Generally,some (maybe not great) advantage to "bigger/faster is better .
Subsequent shots? Recoil/controllability,rapid follow up? Probably 9mm advantage.Three shots 9mm to two 40/45. .Advantage? Determined by organs hit. Speculation useless.
Magazine capacity.Makes zero difference to the Orc being shot until the magazine is empty.Then its important.
There are 7 shot 9mm's and 14 shot 45's. Single vs multiple Orcs.Mag capacity muddies up the water.
Pick the one you likeand believe in.Know the strengths and limitations.Pick one you will carry.Become proficient.Hope you never need it.Be prepared if you do.
In the big picture,IMO,I really don't care if its my 44 Mag Super Blackhawk,my Single Six 32 H+R,my 9mm S+W,or my 1911,or my 9x18 PA 63.
I don't care,and I doubt it will make much difference.
Just let me fill my hand.