Yep
As others have pointed out, most crimes happen in/around the home. A friend's house was broken into a few months back. He was at work and his wife, who'd been on night shift, was at home sleeping at 9am. She woke up to the sound of the alarm. She walked into the hallway (an upstairs hallway that overlooks the downstairs) only to see two guys (looked to be 16-17 years old) walking out with their large TV. She didn't have the gun with her and was reminded later that that's exactly what the gun's for. (Well, rather it, along with the phone, should have gone into the closet, behind locked doors, until the police showed up. But that's another story.) Thankfully, nothing serious happened, and my friend paid $250 out of pocket for a brand new TV, courtesy of his homeowner's policy.
Point being, no one anticipates someone coming into their home. I have two guns I carry in two separate holsters. Either of them fits relatively comfortably. If it's evening and my wife and I are watching TV, the guns might get moved to the table next to me, at a perfect distance for my outstretched right hand to grab without any serious effort. The holsters usually stay IWB until bed.
The other significant factor is that we live in an upstairs duplex. I count on/hope to be able to hear someone coming through the downstairs door (deadbolted), walking up our stairway, and messing with the locked apartment door before I ever need to use my gun. Nonetheless, it's always there. In the shower, it's on the counter, tucked behind some clothes.