Tough choice. If I had to choose only one, it would have to be my Colt King Cobra 4" stainless. My Colt SAA is a close second though, and a friend of mine had a S&W K38 Target Masterpiece that was a dream to shoot.
K-38 Masterpiece is my choice, only problem is at this time I don't have one, I am looking for a good one. I do like all my revolvers for different reasons. If I had to choose one it would be my security six. If I could choose two it would be my security six and my model 60. If I could choose three I would add my super blackhawk in 44 mag.
Best is subjective. My best was a Python I owned about 35 years ago. The one that won me tons of trophys in several disciplines and saved my bacon on duty was a S&W Combat Masterpiece (M15).
Geez, that question covers some ground... all the way from a .22 lr single six to Ruger's latest offerings in Flat Top configuration Blackhawk .44 Specials...forced to pick just one, I'd opt for my 4-5/8" .44 Special BH Flat Top...tho a close 2nd would be a S&W M57 purchased new in 1972. Both are equally accurate, and probably equally deadly in real hand gun terms as well.
I'd waited for a .44 Special for 40+ years, having grown up on Keith's and Skeltons writings back in the 70's. Then, a true .44 Special was only available in S&W's 4" and 6" Model 24's. Skelton had one built up on a S&W Highway Patrolman Model 28, but at a fantastic cost of $125 plus the price of the gun, and a six month wait from the arrogant gunsmith who was doing the reboring and rifling necessary...and with no guarantee on how it'd shoot. (My first encounter with celebrity gunsmiths who's work was trumpeted in the gun mag's).
So I waited, 40+ years...and Ruger finally came through...when it came in to my LGS, I felt like I was ten years old again and opening my first BB gun under the Christmas tree.
To date, that 4-5/8" is my most accurate hand gun...loading for it is ridiculously simple...most any reasonable combination works...here's a pic...good luck finding your "best ever"....and hope you all don't have to wait the forty years that I did.
I never was into S.A. revolvers but was impressed with a Freedom Arms .454 Casull that I had the pleasure to shoot. Over on Cast Boolits the Ruger S.A. revolvers are really popular with us "experienced " shooters. I try to avoid any reference to age...
PzGren, I frequent that forum as well...good info there, especially if you like to throw lead alloy down range. I do like those single actions...tough, ancient design, worn on horseback...hell what's not to like...and Freedom's offerings are top drawer in every respect...I"ve only shot one and it was a beauty. Best Regards, Rod