I spend pretty good money to hunt big Bucks . Sometimes a less than perfect (sometimes a lot less) shot is all you're going to get . I prefer something heavier than a .243 , because I might have to break some bones to get my bullet into the vitals . That's why I like my .358 Win. , it will go through a Deer lengthways , and upset everything along the way ! My .243 will forever be , a varmint gun . I'm at a loss , as to why some guys think it's macho to hunt deer with a cartridge that's marginal for the job , or inadequate , for other than a perfect shot . Up in Ontario , Alberta or anywhere , where large Deer are the target , you will find very few if any .243s !