I'm not sure how well either the Remington duplex HD loads Lance was talking about, or the new Hevi-Shot Personal Defense (or "Maximum Defense" as they seem to be calling it now) round I mentioned earlier penetrate, but after patterning the latter I wasn't too impressed.
At ten yards the Hevi-Shot PD load, with its 35 twenty-caliber T pellets, threw a pattern twelve to fourteen inches wide out of my Mossberg 500 house gun (which is fitted with an old-style 18 1/2" smoothbored, IC-choked "Slugster" barrel). I get pretty much the same results with Winchester number six field loads, for less money. Apparently whatever magic Hevi-Shot uses to make their 3" Dead Coyote round throw tight patterns of T shot is missing from the Personal/Maximum Defense loading.
On the other hand, Federal's low-recoil "tactical" 00 buck round with the FliteControl wad out of the Mossy made one ragged three-inch oblong hole in the target at that distance...most of which, I think, was the wad. And the cheap Estate 00 buck threw a four-inch pattern at ten yards.
I'm still, reluctantly, using that Hevi-Shot ammo for that first round in the magazine - as an apartment dweller, I suspect engagement ranges will be considerably less than ten yards! - but needless to say the next four rounds behind it are all Federal low-recoil buckshot...with five more on the butt cuff.