Im new to the pistol world and chose the ruger sr40c for my carry gun, i chose the 40 because i wanted a bigger hole and more punch than the 9mm and is still semi cheap to shoot. Not a fan of the tried and true .45acp, while it works and people love it. Its just pricey and kind of a -CENSORED--CENSORED--CENSORED--CENSORED- imo, yes it big but its slow. Now i have a hi point 995 carbine in 9mm love the gun and ammo is cheap, but even out of the longer barrel carbine the 9mm is weak. At 20 yards with the sr40c and its 3.5in barrel the bullets rock my steel targets as every bit as hard as the 9mm does out of my carbine at the same distance. So to me there is a huge power difference, but like others have said shoot what your accurate with. A powerfull round is useless if you cant hit the mark. Btw even though im new to the pistol world, im not new to gins and have far to many to list in many different calibers. I also for one would not feel out gunned if i had a .22lr if i knew i could hit the mark!