My thought is that if you hole-up in your room waiting for the cavalry, then the range involved would not yield any significant spread. I am disabled and neither the pump, nor the lever gun, appeal to me. My choice is between a Remington 1100, semiauto 12 gage, and a USGI M1 Carbine, auto loading .30 Carbine, or a Desert Eagle in .357 magnum, with 6" barrel.
I choose the lighter, shorter autoloader for holing up and waiting for the good guys ... the Desert Eagle.
I suspect if those are your only choices you must decide if you can manipulate the lever gun easier than the pump. You do not want any malfunctions under a real ugly situation. Take care of yourself the best you can.