I would think, as long as the bullet holds together, hitting at a faster velocity will cause more significant hydrostatic shock and likely more internal devastation. In the case where a bullet may not hold together, the .300 win mag could be loaded down, or be used with a heavier bullet, which should, at the very least, offer more penetration due to the higher SD bullet. 'Kill better?' I'm not sure about that, if it dies quick and humanely there's no 'better' than that. And .308 should be able to kill most anything with the right load and good bullet placement. There's always the chance that you muck up your shot, and the .300 Win Mag MAY be able to help you there, IF you get lucky. But it's no excuse to take 'bad' or 'lazy' shots. The power of the .300 win mag will obviously not save you 100% of the time with your bad shots, and then there's the fact that .300 win mag recoils more, and is typically harder to shoot, which could increase your chances of making a bad shot, potentially. To imply that the .300 win mag doesn't do more damage than a .308 is plain silly. The difference is, do you really 'need' it, and is it worth the extra recoil? Most hunter don't want to ruin their meat. So 'extra' damage is usually not needed and also not preferred. The fact that the .300 win mag will usually do more 'meat damage' and ruin more meat, is an example of how the .300WM is more powerful, but doesn't necessarily 'kill better.'