Don't underestimate women. . .
Laptop messed up last post.
While yesterday, had I watched the scene unfold, I firmly believed I would have just walked in swinging, If I watched it unfold tomorrow, I hope I will think just a little bit more. I doubt these women are strangers to the full strength blow from a larger man, and the one woman probably outweighed me. During my unarmed combat classes it quickly became apparent that 2 vs 1 was a major gamble. Even with it was a man vs women or a very large individual vs smaller ones. Fighting two people at the same time takes a very high level of skill. I have personally found the only way I have been able to come out of this situation on top is by completely incapacitating the weaker of the two opponents as fast as I can (usually if it took me longer than 20 seconds, I was going to lose) so that I can turn my attention and whats left of my strength to the stronger one.
If they decide to fight instead of run when first faced with the prospect of fighting a man, you may be trouble. Women are generally weaker than men, and a full strength blow might not turn your head too much. But this is still a street fight, and a lethal one at this point. That means there is a high probability that when faced with an opponent that has an extreme physical advantage, the women will do things such as scratch (face, eyes, ears - very, very painful) aim attacks at the genital area (your achilles heel), and probably the worst - bite. Even a smaller woman is going to have enough jaw strength to take a large chunk out of you. The killer about this is that a bite can easily transfer things like HIV/AIDS and other STDS (which these women undoubtedly had).
Initially, I think a knock or two to the head would be sufficient, if it did not end there, I believe an armed response would be appropriate. I can not see a scenario where they would continue to kick the girl in the head when they became aware there was a gun pointed at them, but if they did I feel I would be justified in using lethal force. A punch when standing up is one thing, a kick to the head when on the ground is a different arena.
If all I had was a knife (which I often do, due to the fact that my job does not allow for concealed carry), there would be more than fair warning, then lethal force would be applied with a different platform.