Try to imagine a duel between a guy wielding a .25 Bobcat (the best available .25 or close to it) facing off vs. someone with a Volquartsen .22LR set up for the Steel Challenge. Bonus laughs if Volquartsen guy also happens to be wearing a leather jacket.
Obsessive focus on primer reliability can lead to bad conclusions. Assuming quality ammo, we're talking about a (roughly) 1-in-1,000 event, and when it does occur, it's the simplest of all malfunctions to clear -- it's never a "jam" and takes less than a second to clear.
I'd place my bet on Volquartsen guy, even if I knew half of his (first) magazine was filled with dummy cartridges.