Based on prior comments and previous posts old buddy, I'd say a K frame or L frame would fit you best.
If you could feel a substantial difference in a High Power going from the standard grips to the Spegel thin grips, then you'll appreciate the smaller grips and trigger reach of the K and possibly the L frame (686 & 586).
It's possibly, if your hands are small enough, a J frame - such as a M60 might be a good fit.
Also - the K frames like the 65/66 19, etc. come in two distinctly different (to me anyhow) feeling configurations - a square butt and a round butt.
Aftermarket grips can make a round but simulate a square butt, but, a square butt will always be a square butt.
Personally, I despise the feel of the round butt and the fake feel of the grips that simulate a square butt.
Actually, I despise anything on a S&W except the over sized target grips.
Again - that's personal preference. You mentioned some time ago about a CZ75b not "fitting" you.
I find the square butt K frame (both M19 and M17 (the .22 version)) to have an extremely similar feel to a CZ75B. I can't remember who else here noticed that also.
That being the case, you may like the feel of a round butt frame a lot better.
The big N frame guns, like the M27 and M27 are fine guns. Possibly the best guns ever made in .357 magnum for over all use.
They are on the large side though. I don't find it uncomfortable to shoot my M29 - the .44mag version of the 27/28, but, it's not anywhere near as natural a feel as the M19.
Lastly - a word about the L frame. The L frame feels horrible to me. YMMV and it certainly will. The L and the K frames both share the same grip.
The rest of the frame is slightly larger on the L frame.
A lot of people don't care. A small number of people find it very objectionable. I'm part of the latter.
I don't see why it's such a big deal to the former since it just means on less person they have to compete with for those pristine 586's floating around right?
P.S. One last thing...
You might want to look at getting a Ruger Blackhawk in .357mag also if you go with a K frame or a small J frame.
Neither of those two are happy shooting a steady diet of .357mag in a wide variety of bullet weights.
Good luck - feel free to PM me if there's anything you need me to go into more detail about.