You should have something chambered in 44mag or 454 casull, or even the new 500mag.
Thanks for the tips, but, and there always is a but life, the first handgun that i shot was at 14 years of age, and it was an S&W model 29, 4 screw. I own one of the first original model 500's; it is still Alaska. I use to shoot running jacks with my Colt .45 S.A.A in Avenal California while in the Navy. I have killed bear, deer--muleys and whitetail, elk, Mt. Lion, and various other species with various handguns.
I will carry the 500 for hiking maybe, but in sure Bear company I will use a rifle. Although I consider myself one hell of a shot with a handgun, I shoot a rifle better!!!
Besides, hitting fast moving, large animals in the thick stuff up there with a handgun with your life on the line is no easy task, although it may seem so in your mind. I don't know if you have ever seen some of that thick stuff, but an elephant could charge you from 10 yards, and you would know he was there before he engaged you ... SERIOUSLY.
Take if from me, Elephants in thick stuff are hard to see ... I have been there on foot when I noticed the shadows in betwix the trees were moving ... I went closer to investigate and a herd of ele's was moving by. You, who sit here now and read this may not believe this, but an elephant or a bear is quieter in the thick than a deer!!!
If you are in the open areas where an autoloader may play a factor, or a handgun, most likely you won't need it because when you see them at a distance, they smell or see you ... they leave because they do not feel threatened, you leave because you do!!!
PS: This is not combat ... you have no backup, no suits of armor and your rifle at the ready, predators telling where they are, radios, optics, etc, and you have expectation you are under threat!!!
We are talking about walking the river minding your own Da-- business, rod over your shoulder, warm sun hitting your face, and dreaming of smoked salmon, when you hear a single splash behind you. You turn to see a 1200 pound brownie 7 yards away, one paw in the water (remember what I told you about quiet they are when moving about?), and he looks upset that you are at HIS DINNER WITHOUT AN INVITATION! Unlike your combat with slow as sin humans, this beast can outrun a race horse in a short distance, and this is da-- short! You try to turn on your RED DOT Sight and all you see is brown hair and smell bad breath as the water hemorrages with your red blood like a sunrise over the Northern Transvaal, as he bites you by the neck, cuts your fancy camo sling in two, whilst your extra auto mags hit the water first, and the last thing you think is, "Where in the HILL did he come from" as your vision goes black!
This is not combat, this is survival in a world where you are ON the food chain!