My experience with S&W aemiautos is limited to my duty weapon (4506-1) and handling others at gun stores, ranges and limited shooting of same. To report:
My 4506 is utterly reliable and reasonably accurate (plenty accurate enough for real-world tactical use, probably not for pistol competitions), but it has the ergonomics of a WWI era tank. The gun is a honkin big hand cannon and it just feels cumbersome. It shares the same design 'feature' of most S&W semiautos (esp. single stacks), a grip that was designed by sadists for sadists...narrow as can be with an utterly straight back. This is somewhat alleviated by replacing the factory grips with Hogues, but not completely. Recoil is reasonably mild (it IS a .45, but its also a large .45), but follow-up shot controlability is not all that great...likely a factor of the less than ideal grip and clumsy balance of the gun.
CAVEATS: I am biased. As much as I want to love this gun, I just can't bring myself to do it. Also, reliability isn't exactly 'straight out of the box.' My PD has a team of armorers and gunsmiths to tinker with these puppies, and they go over them with a fine tooth comb every 4 months.
I would never buy one, pre- or post sellout. I think they quit making them, anyway.
Mike
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"A human being should be able to change a diaper, plan an invasion, butcher a hog, conn a ship, design a building, write a sonnet, balance accounts, build a wall, set a bone, comfort the dying, take orders, give orders, cooperate, act alone, solve equations, analyze a new problem, pitch manure, program a computer, cook a tasty meal, fight efficiently, die gallantly. Specialization is for insects." -Robert Heinlein