Well I guess I ought to chime in
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Yeah, I only own one centerfire gun. Period. It's a NewVaq357, heavily modified. The transfer bar safety is intact and factory-stock, and I carry six-up. Loads are by DoubleTap ammo, based on the 125gr Gold Dot slug going fast enough that the energy levels are deep into 10mm territory.
Hammer is the lowered SuperBlackhawk type. I'm a "strong side thumber". At the end of the cocking strong I drop my strong-side thumb off the side of the hammer and right on top of my weak side thumb, both pointing forward, forming a grip in a Weaver-ish hold that is very similar to current thinking on 1911s and the like.
My sights are better than almost any other CCW setup available. Only a glass red dot with conventional backup sights comes close. I use a homebrew clone of the Goshen Enterprises Hexsite:
That's the "Mk4". There's a "Mk5" improved version built but not installed yet. I won't be able to show a picture, because it uses design elements Tim Sheehan at Goshen came up with but hasn't yet published. The holster for it will have to be customized to hide the sight. Yeah, I'm serious
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I do NOT carry in a low-slung "Western" holster. I don't own one and don't like them. If it's at all "jacket weather" it's in a very high-ride-and-forward crossdraw rig of my own design:
In the worst AZ summer months, it's in a fanny pack. With a peace sign on it. Because that's where my piece is
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My thinking goes like this:
First, I like this gun a lot. Best piece I've ever owned and until I can score a Freedom Arms '97, best piece I'm likely to own. I've been shooting it and modifying it since 2005, and it's basically like a part of me now.
I can very quickly and accurately deliver a monster of a first shot. One that sounds like a grenade going off and puts out a big hurt. After that, IF I can keep my head (and I suspect I can), I can deliver more very accurate shots. I'm a "pure sighted fire" shooter who sucks completely at point shooting...sighted fire from a Weaver-ish hold is absolutely the gameplan, along with as much movement as I can scrape together.
Will this solve all problems? Hell no. I full well realize that. But the other thing is, I'm unlikely to get in a mess that six accurate and massively potent shots can't deal with.
And finally, there's that question of "can I shoot it?" I sometimes open carry in AZ. I was talking to somebody at a very gun-friendly store who kinda chuckled at it...and then went serious. I saw exactly what he was looking at.