The Redhawk would have been my choice. The GP100 is too small for a 10mm that you want to shoot full power 10mm loads, Clements states on his site, These guns tend to be very accurate with .40's and 10's and will handle most all commercial ammo. This is a medium frame gun and should be treated as such. Ammo which is loaded to maximum pressure levels should be used sparingly." Clements does quality work and can work this close to the edge but I don't see the lawyers at Ruger thinking that would be a great idea to do on a production basis. The cylinder is just too small on a GP100 for a 6-shot 10mm. Smith used the N frame when they made the 610 for I am sure the same reasons, size and strength.