Re buck460XVR:
"First off, anyone using red locktite on small revolver screws should not be doing their own home gunsmithing. "
It's so funny that you should say this, since if you had read my OP (as others have pointed out), the side-plate screw was factory red locktighted. So, S&W shouldn't be in the business of making guns if that's your logic.
No, my complaint is based on the fact that many of the screws were FACTORY loctited, and I've had to re-locktite them and locktite screws that were not locktited. Yes, I understand that I am new to revolvers. But once again, some people did not fully read my OP:
Re pete2: "First off, it's a lightweight gun, it ain't made of steel, it's a 9mm , it's a new S&W gun." It IS made of steel, except for the cylinder. All of the screws that have backed out are housed in stainless steel.
Regarding oil: No, I have never cleaned the gun or oiled it. This is a factory condition gun that is backing itself out on its own. The only thing that I have done to the gun is fire it and retighten screws, sometimes relocktighting them. But once again, I don't see me not cleaning it to cause the screws to loosen.
RE FUBARness: Yes, I feel the same way, but I am a lucky character, which is why I wanted feedback before I complained to S&W. If the issue is just me "maintaining the gun" by retightening screws every 200-300 rounds (and regluing them), then it could be a side-effect of current revolver production. But this would make me sad. It seems like a number of you recommend sending it back to Smith. This would make more than 50% of the guns I've owned factory defects... sadness...
Re round-type fired through the gun: I've fired +P 400+ ft/lbs 115 grain 9mm FMJ, 147 grain standard pressure TMJ, 115 grain aluminum case standard pressure FMJ, 115 grain standard pressure FMJ, 124 grain +P Golden Sabers, and 147 grain Golden Sabers. None of these rounds were aberrant or non-factory loads. I would doubt that they caused undue vibration or stress on the gun.