Bronson's, er that is, Kersey's Wildey .475 Magnum in Death Wish III must be the coolest.
And there was an HK P9S in St. Ives, and I believe at least 1 or 2 old Bond flicks, used by the villains of course.
It's amazing how many P38s and P08 Lugers were used by villains prior to the '80s. I suppose the obvious Nazi connection was partially behind that....