In an auto, I'd vote for the .32. I, personally don't trust the .380 or any of the other calibers you've mentioned to both expand and penetrate sufficiently out of the short barrels of guns like the LCP, P3AT, and Seecamp and for that reason would use FMJ. If you're just punching holes anyway, the .32 has plenty of penetration with FMJ, is more reliable than a rimfire, has less recoil than a .380, and often holds another round. The penetration of the .25, even with FMJ, is just barely acceptable, and I don't really think that a .355 hole is going to be that much better than a .311 hole so the .32 is the best balance.
Now, if you're looking at revolvers, a good DA .22 Magnum has merit. Even though rimfires typically aren't as reliable as centerfires, a misfire in a DA revolver is cured by another trigger pull. .22 Magnum penetrates adequately and, in the gelatin tests I've seen, often tumbles. The problem is that in a DA revolver the same size as a .22 Magnum, you can get a .38 Special, .32 H&R Magnum, .327 Federal Magnum, 9x19 Parabellum, or .357 Magnum. The only .22 Magnums that are really significantly smaller than a larger caliber revolver are the NAA minis, and a SA revolver doesn't give me the warm and fuzzies when it comes to self-defense.