With press frame lathe mounted on the tool cradle, cutting tool mounted between centers, you get as close to an absloute straight line as is possible on common equipment.
I saw a YouTube video where a home caster melted small engine crankshafts and poured his own press frame, cast steel. Keep in mind the pouring wasn't 'Forged' after the casting, so it *Could* have voids &
fault lines (bubbles & pour line faults).
It looked really interesting, but pouring molten steel isn't something everyone wants to set up for.
I'll cast aluminum & brass, but steel is MUCH more difficult and takes much more time & energy to do.
Figure in the cost & time to cast a press frame, it makes more sense to build a press like the ones shown in pictures above.
The biggest issue I have with 'Co-Axial' type presses is small diameter rods that can stretch & deflect.
The biggest issue I have with 'O' frame presses is small diameter rams, again, deflection.
The second biggest is the length of the guide for the ram, which in industral presses is usually twice the length of the diameter of the ram/rods.
Industral presses often have guides 3X & 4X the diameter of the ram.
It's a surface area/support thing. The small amount of weight & extra material would keep the ram from deflecting, also allow for lubrication groove that would substantially prolong useful life of the press.
Light surface lubrication significantly increases life of presses, we all know that, but industral presses usually have a lubrication delivery groove(s) and a reservoir for continuous delivery.
I think it was Mr. Guffy that commented on knurling to hold grease, but a continuous grease delivery device is a GREAT thing on a press! Positive grease delivery means there is always grease, and where grease is, moisture & crud can't get in...
Now, keep in mind the grease delivery 'Cups' (spring loaded) don't have to be hanging right off the press frame in the way. A grease gun 'Whip' hose is just a few bucks and allows you to remotely locate the 'continuous greaser' so it's not in your way.
These lubricator 'Cups' are called Single Point Lubricator
This link will show you what they look like,
https://weldwarehouse.com/cgi-bin/einstein.pl?::1:WLDWH:1:025=B1741-A
Guys that reload a bunch will appreciate the continuous lubrication...