I have a 10/22, Model 60, and Savage Mark II. None of them are my favorite.
The 10/22 is the LEGO of the .22 world. Easy and fun to work on, and you can turn it in to anything you want. Reliable stock, but does give up some (and just some) accuracy to the Marlin. Both are minute-of-squirrel accurate.
So the Marlin is slightly more accurate, but if you shoot dirty ammo and don't regularly clean out the action it'll start to jam on you. I'm talking 2,000 rounds or so, which may be a lot or a little depending on your shooting and cleaning habits. The Ruger can take a lot more punishment in this regard.
The Savage is a different animal, being a bolt action. It's easily more accurate than both the Ruger and Marlin. My only gripe is the 10 round magazine. For some reason, I prefer a more streamlined look on my rimfires and have never liked those "banana" shaped mags sticking out from the bottom. I picked up a 5 rounder for hunting, which I like a lot better.
As far as my favorite .22 rifle, that honor goes to an old Remington 510 Targetmaster. It's a single shot, but dang is it accurate. If I ever get a second I'll have it drilled and tapped for a scope mount, because I think it'd out shoot my Savage.
But what I REALLY want is a Remington 512 Sportmaster. Same action and barrel as my 510, but with a tube magazine. Should be able to find one in the same price range as a 10/22.