Glock good.... but don't plan on reloading the brass. Swells the bottom due to unsupported region. Cops at my range leave that crap everywhere. I have to inspect everything I pickup.
This issue is easily resolved by getting an aftermarket match barrel. I picked on up from gunbroker.com for $160 shipped. Allows the use of lead bullets + tighter chamber and barrel dimensions = Cheaper reloads for plinking & better accuracy.
Also, it is standard practice for every handloader/reloader that I know to inspect each case before use/reuse... So I don't understand why you consider inspecting Glock-fired brass to be a hassle when you should be inspecting every case anyway...
Wow i am very suprised nobody had said anything about the 1911. I would have to go with a colt 1911 in the great 45 acp, and that is only if i could buy one handgun. You will never need anything more than that, you may want it but you will never need it.
The 1911 is a great gun, but it may not be ideal in this case. It's kind of a complicated gun to get used to, external safties, decocking levers, external hammers, do I carry in condition 1,2,or 3? Am I comfortable carrying in condition 1? I think a much safer gun to get used to for the beginner is a DAO - no external safety, for the simple fact that it requires the shooter to be mindful of the fact that there is no safety other than the one between their ears. It ingrains them with that mindset so that in the future, one would be less likely to depend totally on a gun's external safety to make the gun "safe".
When up against any four-legged predator that could likely eat me, I don't want my only protection to be 7-8 rounds of .45acp. I would much prefer a deep-penetrating round such as the 10mm in a gun that holds 15+1 such as the Glock 20. I'm not a spray-n-pray guy, but I firmly believe that marksmanship coupled with increased mag capacity is better than counting on 5-8 rounds to be enough when the SHTF.
I am a huge fan of the 10mm. In my opinion, it is one of the best rounds ever made and the G20SF (with aftermarket barrel) is the best gun for it. There is a slew of stuff for it: accessories, holsters, barrels, guide rod springs, sights, and the list goes on... Ammunition is a tad more expensive, so if you're planning on shooting a lot and you don't reload; start considering it. I shoot my handloaded plinking rounds for about $.13 each.
I'm a 10mm and G20/G20SF fanatic... But a better choice for you (depending on your size, weight, frame, etc) may be the G29/G29SF in 10mm if you're planning on carrying it concealed. You can still use the G20 magazines in it for when you're hiking and such, but for CCW around town, the G29/G29SF with is a hard gun to beat if you can control it.
Best of luck, hope this helped...