Multiple
As a bonafide rifle looney, there are lots of choices in my safe for deer. Sometimes I'll rest a rifle for a season, others see regular use. Over a 3-1/2 month gun deer season, there's lots of opportunity.
I sort of use the "golf club" approach, in that certain rifles fit the circumstances, or conditions anticipated . Example: One rifle that sees steady use every year since I've bought it is a stainless steel/synthetic Ruger 77MKII in 7.62x39mm. Loaded and scoped, I doubt it weighs more than 6-1/2 lbs, appreciated if hoofing it in a ways. In wet weather, low maintenance required, stainless steel. I don't worry about nicking the boat paddle stock when using a climbing stand, seems like I'm always wacking something with that dang stand on my back. I hunted it just this AM. Didn't see nothing.
I'll set another rifle out for longer ranges, when hunting the R.O.W;s near my home. For that, there's a Walmart Rem 700ADL in .270 and a 3-9x scope, and recently, a .308 Savage Hog Rifle too, with a 6x42 on it. Both of those are on deck this year, but the .270 has not been afield.
I've got some genuine brush rifles as well, and one of those generally will see use through the season, a scoped Mini 30, or a pair (one scoped the other with XS sights) older Ruger .44 carbines. This year the XS .44 has taken a rather unlucky 5pt, who had a worse morning than I did, after running out of gas on the ATV, killing the battery attempting to restart, than finding someone already hunting my desired spot. Took a walk primarily to scout in new territory, and along he came. Likely the last deer I will ever kill with peep sights.
Finally, I have an nostalgic streak, and will hunt a few rifles for sentimental reasons. The highlight of this year so far has been another buck that fell to my Grandads 1956 Winchester 88/.308. The old lever rifle has not spoken for blood in a long time. My notes show that the last deer I killed with it was Thanksgiving Day, 1993!!! That's 22 seasons ago. Basically retired as a family heirloom, I rescoped it this fall with a Leupold 6x36 (the old Bushnell Scopechief my Dad put on it was just not bright enough anymore) and took a small 3 pt meat buck for a disabled friend last Sunday with an easy 45 yd shot from a shooting house.
Hmm......! Should I hunt tomorrow........what rifle?