I ran some Hornady CD thru my M66 3". It was very mild, though it only chrono'd at 945 fps--not a lot for a 110 gr. bullet. Not to say it wouldn't be an option. Obviously, this was the std. pressure stuff.
That's actually not half bad. Federal's 110gr "Personal Defense hydrashock" would have a hard time hitting 850 from that length and era S&W barrel.
A more modern S&W barrel or a Ruger barrel (any vintage) would likely shoot faster for the same length and you'd probably break into the 1,000fps range.
It's always worth knowing about effective "granny loads". You never know when your own wrists/hands could suffer damage, or you need to help arm/train somebody with recoil issues.