For a multi-purpose pistol that might be carried into the boonies, I'd like to have it de-horned for comfort and finished in Metalloy (hard chrome) for durability.
And if I were spending the big bucks for a custom pistol, I'd also want a checkered (or possibly stippled) frontstrap, carbon fiber stock panels (for durability and a little extra safety in the event of a ruptured case), and either low-mounted adjustable sights or some sort of night sights, depending on whether target shooting or self defense were a higher priority. And I'd also want an arched mainspring housing, something none of the non-custom, high end builders offers (as far as I know).
If there's a Wilson pistol that fits that bill, I might buy it, or I might have a gunsmith build me a pistol from a Rock River or Caspian slide and frame set.