For me it isn't the Glock grip angle (had a pair of Steyr's in the past), but more so the finger grooves and trigger guard on the compact and subcompact models; the 19 and 26 in my case. I would get a serious case of "Glock Knuckle" from the trigger guard after firing just a couple of magazines, and then dealing with the finger grooves being so close, crammed my fingers by being forced together.
So, like others, I would simply get rid of them, which in my case is/was a mistake because I shoot Glocks just as well as the other pistols I have dealt with, regardless of grip angle, trigger type, etc. Now granted, I don't have any issue with the full size models, with exception of the trigger guard and pistol grip junction, but I simply prefer the smaller models.
So, when I acquired my fourth Glock a couple of weeks ago in the form of another Gen 4 19, I promised myself not to get rid of it, and that I would do the necessary grip mods that I had always talked of doing, but never did, along with adding the orange front Trijicon HD night sights.
Now it's still not, nor will ever be as natural pointing and feeling as my CZ P-07 or CZ 100, but the mods made a very noticeable and improved difference, especially when I draw from the holster. I'm no longer fighting with grooves trying to control where my fingers naturally wrap around the grip. This one's now a keeper.