I first shot a Gummint .45 some 50 years ago, as well as a Luger and a P-38. I've had S&Ws, Glocks, and a 92S. I've enjoyed Commanders, LW Commanders and a Delta Elite.
My hand is happiest with the feel of the Government "handle", as well as the single action trigger. Since it's as accurate and reliable as any other pistol I've ever shot, I've never seen any need to bother with "other stuff".
I'm dubious that my near-67 years is as much of a factor as are the experiences of my first years of shooting...
FWIW, Art