I hunt with my 480 Ruger Super RedHawks.
Ammo Availability??? I have never fired a factory round through either of mine. With around 300 pieces of brass, and 3 bullet moulds, I should never have an ammo problem.
The very first thing I do with a Super RedHawk, is replace the wood insert factory grips with Hogue "Tamer" grips. The "Tamers" have a Smurf Blue Sorbothane strip down the inside of the back strap to soak up recoil. Originally they were offered from the factory on the Alaskan's. My brother just got a New 44 Magnum SRH, and it had the Hogue "Tamers" on it from the factory. NOTE: Some factory grips may be Hogue Rubber, but not the Tamer version on older models.
I really like the 480 Super RedHawk. They have a Quick Change front sight on older models. I change the front sight to a Marble Green Fiber Optic for back up.
As was said above, I swap the grips for Tamers.
A set of Wolff springs is a nice addition.
The Ruger is easy to work on.
I have a 30mm UltraDot Red Dot optical sight on my 9.5" one, in Ruger 30mm Factory Rings. I have the 25mm (1") UltraDot on my 7.5" version. The 30mm is much better, with a lot more field of view.
We set my brothers 44 up with a Weigand scope base, and a 30mm MatchDot II.
The UltraDot just has a single 4 MOA Dot size. The MatchDot II has multiple Dot Sizes, 2 MOA being the one to use in the woods hunting. So far the Match Dot II looks like a better choice. Not sure if it will fit between factory rings however. I need to measure my brothers and see if it will fit.
The load I am using at the moment is a 375 grain WFP Gas Check Mountain Mould bullet I designed myself with 70% Meplate. I am using 18.5 grains of Lil Gun with WLP primers. This is a 1200 fps load from the 9.5" barrel. Plenty Bad enough for any deer. I have had this bullet up to 1,414 fps. It is not a lot of fun to shoot that hot.
My advice would be to get a set of reloading dies, and some Starline Brass, and start reloading for the 480R. The 480 uses standard Large Pistol Primers. Magnums are recommended for some powders. It is pretty straight forward to load for. Think of a larger 45 Colt or 44 Magnum.
Reloading beats ammo not being in stock, not to mention $40 some odd $$$ a box of 20 for factory ammo.
Bob