did you catch this?
The OP stated a "medium size 4-6 inch .44 mag"...... and there's hardly any such critter!
Most .44's, double actions anyhow, are pretty beefy guns. A S&W Mtn revolver, 4" comes closest to the concept, but that still pretty chunky when compared to a K-frame or similar.
Now, a single action, fixed sights, something like a Vaquero, or a Blackhawk, down the lines of a Colt SA, (my Dad had a Hawes Marshal for awhile) are fairly portable, but still not in the same league as a M19, a Sec-6, etc. I'm not even sure the Vacquero is available in .44 mag?
Handloading a .44 mag up and down makes it pretty versatile, but you can't escape the fact that .44 mag class revolvers are big! Carried for extended periods, or any distance, even in a exposed, field type holster (the OP was not interested in concealment) will give the medium frame .357 a bit of an edge in convenience and portability over a .44.