By tougher shots I mean shots where the angle isn't perfect or you might have to penetrate a shoulder. Please note that I do NOT mean "Texas heart shots" or any similar foolishness.
Given the right bullet, will a .243 not penetrate a shoulder at 200 yds or less...?
You can parse my posts looking for nits to pick, but 20% heavier bullet, more frontal area, better sectional density are all real world advantages for the 25-06. If you want to make an argument for the 243, please explain how it is in some way superior to the 25-06, not just "almost as good as".
That's sort of the point...how good or superior does it have to be for this purpose?