I think a lightweight Colt Commander is one of the best choices. I had one that was perfect but I don't know why I don't have one now, though I am going shopping in a few minutes. As another pointed out, they are not inexpensive. And a lightweight Commander model is sufficiently sturdy to stand up to as much shooting as most people can afford.
For a while, Colt made a full-size lightweight Government Model but I'm not sure I ever saw one (they didn't look any different). However, the regular full sized model will start feeling heavy after a while. But everything said about them a hundred years ago is still true. While they have a relatively long barrel and the grip is maybe a half-inch or so longer, they are flatter than most recently introduced pistols.
For a while, Colt made a full-size lightweight Government Model but I'm not sure I ever saw one (they didn't look any different). However, the regular full sized model will start feeling heavy after a while. But everything said about them a hundred years ago is still true. While they have a relatively long barrel and the grip is maybe a half-inch or so longer, they are flatter than most recently introduced pistols.