For HD, inside a home, in order of preference.
*Handgun: Realistically this is going to be the better option inside a home.
*Carbine: Caliber doesn't matter much, 30 Carbine, 223, any pistol caliber etc.
*Shotgun: 9 pellets of 00 buck.
This load already has 300 WM recoil levels, the larger magnum loads are approaching, or exceed 458 WM recoil levels from a typical weight shotgun and the negatives outweigh the positives.
If 00 buck isn't available, then any standard 2 3/4" load with the biggest shot size available.