I've tested a few powders for .38 Special for 110, 125 and 158 grain bullets. The best by far has been AA#2 powder using Accurate Arms data. Most uniform velocities and good accuracy. Even Unique powder gives wider velocity ranges and Blue Dot is absolutely the worst powder for .38 Special. I've personally seen blooper loads with Blue Dot that you can see the bullet in the air and see it hit the ground way short of the target. I'd pick AA#2 or Bullseye or similar faster burning powder. The long case with some powders especially slower pistol powders I don't think ignites well with most of the power up next to the bullet? Just be careful and prevent double charges in .38 Special as most powders do not fill the case.