AFAIK, the XS rail's forward end is anchored in the rear sight dovetail, not the front, and I suppose you could attach it sans Loc-Tite for easy removal -
but -
The Loc-Tite's used for a reason - recoil.
Keep in mind the Guide Gun's chambers in .45-70, and that a 300-400 + gr boolit's no slouch, when it comes to the jarring vibrations the loosen scopes & mounts tuit' suite - to the point of losing zero very rapidly.
FWIW - there's lotsa folks who suppose this/that, before they ever own/use something, and overthink it.
Chances are, once the XS rail's mounted, you'll either remove it permanently, or always use it - either with a Scout scope, or in conjunction with the XS peep that mounts on the rear end of the rail.
In my case, I liked the Scout scope so much, that I removed the iron sights from my Marlin entirely - and haven't had an equipment issue in the 6+ years I've been hunting the combo like that. (Top rifle, below)
In your case, the longer XS rail can be installed (It extends back past the rear scope mount holes), with both a Scout scope AND the XS rail ghost ring peep sight mounted on it - that way, only the scope would needs be QD'd if/when the use of the peep's desired.
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