Many of my buddies that reload, me included, think the time to convert a caliber is really irrelevent ....because we reload on progressive machines ( 650's, LNL, 550's, etc )...and we generally load 30 - 40 boxes at one time, box them and pull from inventory for weekly range trips.
Most of us reload 8 - 10 calibers....but when we convert calibers...we take the time to clean dies and toolheads, clean and lube the press, clean the casefeeder, empty and clean the powder measure and disassemble and clean the primer feed mechanism......and most of us have quick change kits for each caliber ( dies, powder measures and powder check dies installed in the specific caliber toolhead on the shelf )... so we clean as we break it down...and the next caliber up is clean and ready to go.
Breaking the press down, clean & lubing might take 30 min...but its really not a big deal because it isn't like you are liable to only run 4 boxes, break it down & run 4 of another caliber...you could do that change on a 650 in 10 minutes...but its not the way most of us run our hobby.
As an example my press was setup this am in 9mm...I loaded about 15 boxes in an hour or so after breakfast while i had some free time.....case gagued them...boxed em up.... / put 5 boxes in my range bag for practice today and put the other 10 in inventory for another day....right now my handgun ammo inventory looks like this:
60 boxes of 9mm ( I shoot 10 boxes a week )... so 6 wks inventory
40 boxes of .357 mag .. ( I shoot about 6 boxes a month -- 6 months inventory)
30 boxes .40 S&W ...I shoot about 10 per year
40 boxes of .45acp...I shoot about 40 boxes a yr
12 boxes of .44 mag....i shoot about 5 boxes a yr
20 boxes of .38 spl ( keep it for grandkids ...probably 10 bx a yr)
40 boxes of .380....( couple people in my family shoot 6 - 8 bx a yr...
I keep bullets for each caliber, powder, etc....but 90% of the time my press stays in 9mm mode...unless I need to replenish inventory....kids or grandkids visiting...son & daughter in law want to go to range, etc...
All my buddies are similar ....some of them shoot mostly .45acp.....or .40 S&W....so their inventories reflect their trends...
Wed...i'm meeting some buddies at range ...for some revolver drills...so I'll take 2 or 3 .357 mag revolvers out and probably 6 boxes of .357 mag... / when my inventory on .357 mag gets down to about 10 boxes, i'll setup press to run 30 or 40 boxes ....so i just need to make sure i have a few thousand bullets & a tub of cleaned and sorted brass ( and I do )....
In general, i break the 650 press down for cleaning & lube about every 3,000 rds regardless if i change calibers or not...