In 2008 my unit was issued '43 vintage API-T from (if I remember right) Des Moines Ammunition Plant (ammo issued for training since Mk 211 is a dud producing round, which makes going down range to move unknown-distance steel targets tricky . . .). After firing a small number of rounds we had multiple rounds fail catastrophically and apparently come apart in midair within about 100 meters of the muzzle.
This was not a comforting development. And to be fair, it may have been just related to the tracer element, not the complete bullet, but the spotters manning those guns didn't see splash anywhere in their field of view on the targets -- so if the bullets were making it downrange they were triple or quadruple digit MOA kind of accuracy. The ammo in question had passed all the military QC checks for long term storage, etc., but we flagged the whole lot as bad and it got pulled from use. (Probably eventually reapproved for training only, but our training event was over and finished before that decision got made one way or another.)