I have a 442 and like it, but then, the LCR was a few years off when I got my 442. If I was buying now, I'm not sure which I'd pick. I like the looks of a metal revolver better than polymer, but I love that the LCR can be had with an XS nightsight.
Then again, after several years with my 442 as my pocket gun, my SIG 290RS, Kel Tec Pf-9 (assuming it proves reliable enough, jury is still out) and Ruger LCP are all so concealable, and much more pleasant to shoot, that I'm considering selling my 442. I may go to steel framed snubs only (I love my Taurus 85CH as an IWB gun) and going autos only for my pocket guns. The pocket 9mms and .380s and certainly the heavier steel framed snubs are so much more pleasant to shoot, and have much quicker and more accurate follow up shots, than the lightweight snubs. So, I guess really, if I was doing it again but armed with my current experience, I'd get a pocket 9mm and/or another steel framed snub (actually, I would have done that when I got my 442, but there were no affordable pocket 9's yet, the Kahr PM9 and Rohrbaugh we about the only optoins).
Now, back to your question...Handle them both (and preferably, rent them and try them both if you can) and see which you prefer. Both will be good guns for their purpose (though far from fun to shoot). Though, if you want the nightsight, and don't want to pay a small fortune for one of the handful of specialty model S&W snubs with a nightsight or fiber optic sight, you may be better off going with the Ruger.