The part that's radical about my shooting is that I focus on the target, not on the front sight.
Really depends on your individual needs. What's best for one is not necessarily best for all, no matter how good they are. Different needs, different stances. How a competitive autopistol shooter holds his mousefart-dribbling automatic is of no consequence if you're shooting a heavy recoiling sixgun. Try to muscle against the .44Mag and above with an isosceles stance and it's gonna hurt.Visit your local USPSA club and go see how the absolute best group of shooters in the world hold their guns.
Now, I've been concentrating on one handed because I feel that it's more practical.