I used to have a 14' python back many years ago when I was a teacher. Handled it many times & had kids as young as 1st grade handle it too. I controlled the head, and lined up a dozen or more kids to hold the body. It made a nice show.
That said, I have pretty good memory of how thick the skin was.
If it were me, I'd go 00 Buck. 4 buck might do the job, but if you want to kill it, kill it dead. At 12' you're going to get about, what... 2 and a half inch pattern with 00 buck? That would be perfect if you put it on target.
Personally I wouldn't take a chance with something light like birdshot if I had 00 in hand. Why have to shoot it more than once right?
That said, I have pretty good memory of how thick the skin was.
If it were me, I'd go 00 Buck. 4 buck might do the job, but if you want to kill it, kill it dead. At 12' you're going to get about, what... 2 and a half inch pattern with 00 buck? That would be perfect if you put it on target.
Personally I wouldn't take a chance with something light like birdshot if I had 00 in hand. Why have to shoot it more than once right?