P220/45ACP, extra mag or two, Victorianox large folder, Leatherman Blast, wallet, occasionally a small light. Try to live up to the Boy Scout motto: Always be prepared.
My EDC gun is a Kimber Stainless Steel Pro Carry riding in a Galco OWB holster. On the non-shooting side is two Wilson Combat 8 round mags in a Galco dual Mag carrier. Clipped to the inside of my strong side pocket is a folding knife.
Every once is a great while, depending upon where I am traveling, I will add a second dual Mag carrier with two additional Wilson Combat 8 round mags.
When on a road trip, I will take a second gun for the car, usually a Glock 36 or 21.
Currently, either a Glock 42 or 43(depending on attire and carry method); along with a Microtech Ultratech double edge OTF knife, and a Streamlight ProTac 1L light. In winter weather, I carry my Glock 30SF.
My EDC: Glock 27 loaded with Federal HSTs in a Don Hume IWB holster. Kershaw-Emerson CQC-4k, wallet, keys, iPhone 5S. I also carry a Pelican 2360 flashlight but only at night.
Cant manage much more than that without my pockets being too full.
In the winter I will sometimes wear a larger gun and mag carrier, this winter I was sometimes carrying my Glock 17 ODB with a couple spare mags on my belt.