The only Glock I own is a Gen 4 Glock 19. The changes I have made to it are as follows:
1. Frame modification: took off the GD finger grooves, undercut the back of the trigger guard, and stippled the front strap after smoothing of the finger bumps with a wood burning iron. I did not regard this as an option. The finger grooves on the G 19 just plain don't fit my hand.
2. Trigger modifications: replaced trigger/trigger bar assembly with a smooth face Gen 3 assembly. I dislike the serrated trigger shoe face that is standard on the Gen 4 Glock. Polished the internals. Replaced stock disconnector with Glock OEM "minus" connector but also replaced stock trigger spring with a NY-1 spring. This results in a somewhat heavier trigger break but firms up the miserably spongy pre-travel on the stock Glock trigger.
3. Sights: like many I feel the stock polymer Glock sights are crap. I choose an Ameriglo Spaulding set with a tritium bead front sight surrounded by an orange rectangle, and blacked-out, serrated rear sight.
4. Glock striker control device, otherwise known as "Glock Gadget". This replaces the slide back plate with one that has a hinged center that goes back as the trigger completes cocking the striker. This allows one the ride the back plate with the thumb while holstering in much the same manner as hammer-fired pistol owners ride the hammer while reholstering, reducing the chances of a foreign object in or entering the holster pulling the trigger resulting in an AD.
5. Modified slide lock lever and slide catch/release lever with larger external tabs. Not essential but just makes the operation of the pistol a little easier.