Dave,
There must be somebody who's had an AD with a DAO compact other than a Glock, but I don't recall reading or hearing about them.
Even the PPK can be made safer by replacing the cartridges with snap caps, filing 1/4" off the business end of the firing pin, and plugging the barrel. ;-) The question is, however, what is reasonable, effective, and utilititarian "safe" for a CCW?
Don't get me wrong. I don't think any DA/SA pistol should be carried chambered and cocked without a manual safety engaged.
Human factors engineering refutes your belief that "there is a time penalty in a serious situation, provided the user has practiced the draw/safety/discharge process properly" on two counts. First, the "serious situation" isn't something you can effectively practice for, so the more complex the movements the greater the liklihood of messing up becomes.
Second, to draw and fire DAO is a single fluid movement with all the muscles of the hand progressively going in one direction to grab, grip, and pull the trigger. The PPK DA plus safety requires grab, push (thumb in the opposite direction), grip, and pull the trigger.
If somebody can draw and fire the PPK your way in .5 second, they can do it without the safety in much less time. There's just no way around that!
If the PPK had a reasonable DA trigger pull of about half of what it is (say 7-9# instead of 19+#), you'd even have a decent chance of hitting your target. In a serious situation with the PPK, your second shot is likely to be screwed up by your overcompensating for the first one! That you can fix -- by adding yet another step to your draw and fire drill. It would be grab, push (thumb in opposite direction), cock (thumb in different plane and direction), grip, and pull the trigger.
If stuck with a PPK as a CCW, that's how I'd practice. I'd have a better chance of getting the first shot on target, and there wouldn't be any difference on how the pistol operated for subsequent shots.
However, by putting the PPK into somebody else's eager hands, I won't be faced with that. I'll stick to my finely tuned and 100% reliable P11, which has zero configuration or force problems and more rounds of a more potent cartridge. I also won't be faced with the possibility of my bride being unable to defend herself because she just couldn't operate the thing in a HD situation....